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Why Retroviruses Appear in AIDS, Cancer andAutoimmune Diseases
part 1 | part 2 | part 3
By Cal Crilly, 27 May 2006 edited by Fintan Dunne, Editor MyLongLife.com www.newmediaexplorer.org/sepp/2006/05/30/ why_retroviruses_appear_in_aids_cancer_and_autoimmune_diseases.htm
Section 11
Benzene and a lot of the chemicals we use mangle this differentiation. And that includes AIDS and Cancer drugs.
A month after September 11 happened I was a mess because of this and rocked up to 3 different doctors until the third diagnosed pustular psoriasis. That meant every one of my pores was breaking out in pus or white blood cells.
I had fevers and chills, rapid weight loss and no sleep.
My doctor also treats AIDS patients. If I wasn't in a long-term relationship at the time and had taken a HIV test at the start years before I could have been in trouble if I'd taken the test. I knew it was all rubbish when I sat itching in his surgery so I didn't. But here is the nerd stuff on autoimmune diseases that cross react with the HIV test.
Hold on to your hats, it makes me tired just looking, it's night time and I'm putting on my sunnies.
So my first point is that DNA Hypomethylation is a major cause of autoimmunity.
"These drugs also induce an autoimmune syndrome, suggesting a possible relationship between DNA hypomethylation, T cell autoreactivity, and certain autoimmune diseases. To test this relationship, DNA methylation was studied in T cells from patients with rheumatoid arthritis and patients with systemic lupus erythematosus, and was found to be impaired. These results support a relationship between DNA hypomethylation and some forms of autoimmune disease."
Now the stuff on how HIV test cross-reacts with the retroviruses that turn up in autoimmune diseases.
"In 8 out of 29 patients with scleroderma we found antibodies to HIV retroviral proteins in the Western blot analysis. The sera each reacted only to one or two of the p 18, p 24, p 55, and p 65 bands, and the reactions were relatively weak.
The first set of experiments performed on four patients with Sjogren's syndrome (SjS) and four patients with systemic lupus erythematosus (SLE) revealed a significant anti-gp120 antibody reactivity in autoimmune patients when compared to healthy HIV-negative controls.
A significant anti-p24 reactivity was observed in 18 of 29 sera from SjS patients and in 13 of 25 sera from SLE patients.
RESULTS: Sera from five of 15 patients with Sjogren's syndrome (33%) reacted against p24 group specific antigen (gag) of human immunodeficiency virus (HIV). Labial salivary gland biopsy specimens from seven of the 15 patients with Sjogren's syndrome (47%) contained an epithelial cytoplasmic protein reactive with a monoclonal antibody to p24 of HIV.
We previously reported that 30% of SS patients and 36% of systemic lupus erythematosus (SLE) patients have serum antibodies to the p24 gag protein of HIV-1.
The p24 gag protein shares a proline-rich epitope with the Sm nucleoprotein to which many SLE patients have antibodies.
RESULTS. Antibodies to retroviral proteins (ARP), most frequently to HIV Gag proteins p55 and p24, were found in 64% of 22 patients with systemic lupus erythematosus (SLE), in 63% of 8 patients with discoid LE (DLE), in 75% of 8 patients with mixed connective tissue disease (MCTD), and in 26% of 19 individuals with chronic biologically false-positive (CBFP) seroreactions, but not in 8 patients with subacute cutaneous lupus erythematosus.
A review of the cases of 20 Zimbabwean patients with acute arthritis raises the possibility of an association between arthropathy, immunogenetic factors, and human immunodeficiency virus (HIV) infection.
Of note was the finding that, of the 19 patients screened, 14 (74%) showed antibodies to HIV and 11 exhibited some features of acquired immunodeficiency syndrome (AIDS)-related complex, especially weight loss, fever, and generalized lymphadenopathy. No HIV- positive patient was a homosexual, intravenous drug abuser, or blood transfusion recipient. Since the 74% prevalence of HIV antibodies in this series exceeds that found even in high-risk populations (e.g., 18% among patients attending sexually transmitted disease clinics in Harare), it seems unlikely to be a chance finding."
Hepatitis C is not isolated just as HIV is not isolated, really hep C is an autoimmune disease just like lupus. In fact hep C is lupus.
"On Southern blotting of DNA extracted from thyroid glands of five patients with Graves' disease, two probes (720 bp and 942 bp) for gag human immunodeficiency virus type 1 (HIV-1) gave a positive hybridisation signal in all samples tested.
Hepatitis C virus was detected in the serum of three of these four subjects, all of whom had Graves' disease.
Both ELISA and the Immunoblot assays may be falsely positive for ongoing HCV infection in patients with SLE. Suspected HCV infection should be confirmed with PCR for serum HCV RNA in these patients."
Here's my point again about DNA hypomethylation causing the problem in lupus, HIV and hep C and all the autoimmune diseases.
"T cells from patients with lupus exhibit diminished levels of DNA methyltransferase (MTase) enzyme activity, hypomethylated DNA, and changes in gene expression similar to those exhibited by T cells treated with methylation inhibitors, suggesting that DNA hypomethylation may contribute to human lupus."
I had the symptoms of Grave's disease or hyperthyroidism. Ugh.
"Graves' disease are identical to the symptoms of hyperthyroidism, a condition that can be caused by Graves' disease. Classic symptoms include an enlarged thyroid gland (goiter), nervousness, heat intolerance, weight loss, sweating, diarrhea, tremors, palpitations and exophthalmos (swelling of the tissue behind the eyeballs causing protrusion of the eyeball)."
Selenium, copper and iodine are needed to balance Thyroid function. Women with periods that are going out of time need to get these nutrients into their diet because that's how it's all balanced. I munched Brazil nuts to get my copper and selenium and it worked.
This is what they say about false positives from a HIV test. Oh God.
"There are many possible reasons for an indeterminate HIV antibody Western blot assay. Some of these reasons might be: Prior blood transfusions, even with non-HIV-1 infected blood; Prior or current infection with syphilis; Prior or current infection with malaria parasites. Autoimmune disease (e.g. diabetes, Grave's disease, etc). Infection with other human retroviruses such as HIV-2, HTLV I/II. Association with "large animals." Animal trainers and veterinarians are sometimes exposed to viruses which do not cause human disease but may interfere with HIV antibody tests. Second or subsequent pregnancies in women."
Here is an example of "Second or subsequent pregnancies in women.
"Expression of intact endogenous retroviruses by normal placental villous trophoblast and immuno-crossreactivity of villous trophoblast with anti-retroviral antisera have been documented."
Trophoblasts are fetal cells.
Section 12
Well, it's obvious that the claim about the HIV test being specific is just a claim. The p24 core protein is all over the place, how did they get away with this?
"A major core protein of the human immunodeficiency virus encoded by the HIV gag gene. HIV-seropositive individuals mount a significant immune response to p24 and thus detection of antibodies to p24 is one basis for determining HIV infection by ELISA and Western blot assays."In fact three quarters of the population have antibodies to the p24 protein, this is because we eat cows and drink milk and this is nothing new. The only reason we have antibodies is because the Bovine Leukemia Virus is from a cow and so we make antibodies to a retrovirus from a different animal, why would we allow a cow retrovirus to replicate in us.
But it doesn't cause Leukemia in humans or cattle, because when a cow gets low in the nutrients that enable DNA methylation - as we should know now hypomethylation happens and the Bovine Leukemia Virus comes out, it is not the cause.
"Using immunoblotting to test the sera of 257 humans for antibodies of four isotypes (IgG1, IgM, IgA, and IgG4) to the BLV capsid antigen (p24), we detected at least one antibody isotype reactive with BLV in 74% of the human sera tested."
This is why they say this.
"Association with "large animals." Animal trainers and veterinarians are sometimes exposed to viruses which do not cause human disease but may interfere with HIV antibody tests."
If you hang round with different animals you can develop antibodies to their transposable elements if of course they get into you. Sometimes it may be a problem but that's why our DNA methylates to protect us from them.
The scary thing is that cancer patients can be HIV positive.
"In previous studies we found that many humans had antibodies to BLV envelope glycoprotein (gp51) and capsid protein (p24), suggesting humans might possibly be infected with BLV.
This is the first report of human sera with antibody to BIV-specific proteins.
RAK antigens p120, p42, and p25 exhibit molecular and immunological similarity to the proteins encoded by human immunodeficiency virus type 1 (HIV-1) and are expressed by 95% of breast and gynecological cancer cases in women and prostate cancer cases in men.
PCR with HIV-1 Env-derived primers revealed DNA sequences with over 90% homology to HIV-1 gp41 in syncytia and in ovarian cancer cells but not in normal ovary cells."
This one made me laugh, those damned mice giving us cancer.
"In addition, the presence of HERV-Ks, which are homologous to MMTV (11, 12, 13) , has made it difficult to distinguish between endogenous and exogenous MMTV-like sequences."
Section 13
The HIV antibody test unlike all others has to be diluted. This is because we are all positive and we are all positive --because the HIV antibody test just picks up any old retrovirus. And we are full of them.
"I first took samples of blood that, at 1:400 dilution, tested negative for antibodies to HIV. I then ran the exact same serum samples through the test again, but this time without diluting them. Tested straight, they all came positive."The viral load test used for HIV detection is for a thing called Reverse Transcriptase that indicates how much retrovirus is floating around inside you. But HERV-K again uses the stuff and you've seen enough HERV-K blah from me to sink a ship. And HERV-K appears in all of our diseases plus pregnancy which last time I looked wasn't meant to be a disease. Some women may disagree.
"These combined results may suggest that these endogenous RT enzymes still have a biological function."
So how do we quietly put the HIV/AIDS industry to sleep for being so out of date, boringly repetitive and downright deadly? I don't know because the idiots who run this show get 28 billion dollars in funding from the American taxpayers. What a mess and what about Robert Gallo? If you were getting $150, 000 a year would you put your hand up and say: "I made a boo-boo"?
"The NIH says the HIV-1 patent is one of its most lucrative, bringing in millions of dollars a year in licensing fees. Robert Gallo, an NIH scientist who shares credit for discovering the HIV-1 virus, says he reaps $150,000 a year from royalties -- the maximum allowed by United States law for a government scientist.
Gallo is the co-discoverer of the AIDS virus. Cross Atlantic doesn't typically invest in bioscience companies, Fox said, but has in this case because of the scientific pedigree of Gallo and his team. "Ultimately in venture capital, you invest in people," he added.
The discretionary FY 2005 budget request for the NIH is $28,607 million."
It won't go quietly will it?
This is a Professor from the University of Queensland here in Brisbane, where I borrowed John Lauritsen's 'AIDS War' from and ended up in front of this computer screen going nuts. I read that book in 1998, I can't help it, Lauritsen was angrier than me and saw this whole scam happen to his gay community and he was screaming. I just got damaged reading it.
John Mattick has some good ideas, and this is what he says about our friendly transposable elements.
"Mattick has evidence that RNA molecules wield ultimate control over when and where genes switch on and off. By switching integrated networks of genes on, and switching others off, RNAs control cell identity. They sculpt the myriad specialised cells of the immune and blood systems, make heart cells for hearts, nerve cells for brains, and liver cells for livers. RNAs also co-ordinate the miraculous development process of growth and differentiation that builds a perfect human baby from a few anonymous embryonic cells.
If Mattick is right - and his evidence persuades a growing number of colleagues that he is - the descendants of his DNA-parasitic "hobos" are the "gnomes of the genome", toiling away unnoticed in the city of the cell, organising and running the whole, wondrous shebang."
I'm not a health guru, this week I've eaten sandwiches for lunch, eggs and beans, eggs and veggie sausages twice, eggs and salmon from a can, pasta twice because I spent my spare cash seeing the Zoobombs, a great Japanese band two weeks back. My bag of lemons kept me going this week. Remember the profound influence of hormones?
Well, thinking about this has frazzled me probably for years. Right now I haven't slept, I feel ill and stressed but I'm alright. I don't have the sort of stress you get if someone tells you you're going to die because of an outdated test.
Tonight I have to practice with my band, tomorrow I sleep and then see the lovable legend of Brisbane, JJ Speedball, doing his cherry rock for a laugh.When I press send on this I'll be happy as... because it will then be everyone's problem, not mine to think about.
I just want someone else to notice because we are all in danger if we don't get moving to shove this monster in a coffin, stake it through the heart and nail it down hard before turfing it in the ground and pouring concrete over the top.
CU's Cal
See Also: AIDS - Retrovirus Expression Regulated by Methylation? by Cal Crilly May 18 2006
Glutathione Peroxidase - selenium, Aminoacids Overcome AIDS OMNS April 26 2006
Will Nano selenium Help Prevent Avian Pandemic? by Qu Yuan, Qu Lai and Qu Shaozhong, February 17 2006
Note: We highly recommend you read the original article at www.newmediaexplorer.org/sepp/2006/05/30/ why_retroviruses_appear_in_aids_cancer_and_autoimmune_diseases.htm for the many additional supporting links and references it contains. |

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